Liver Fibrosis
~ by Jo Jordan
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Fibrosis means the formation of fibroids or fibrous tissue, usually in reference to the development of tissue at a wound site resulting in the formation of a scar.
Liver fibrosis, also known as cirrhosis, is characterized by the formation of fibrous tissue, regenerative nodules, and liver scarring, all of which interfere with blood circulation, leading to progressive loss of liver function.
Commonly caused by alcoholism and hepatitis C, cirrhosis is a degenerative disease of the liver. Other causes of liver fibrosis include,
- Autoimmune hepatitis
- Blocked bile ducts
- Chronic hepatitis B and D
- Exposure to toxins such as alcohol, certain pharmaceutical drugs, and infections
- Inherited illnesses such as alpha-1 antitrypsin deficiency, hemochromatosis, Wilson’s disease, galactosemia, and glycogen storage diseases
- Nonalcoholic steatohepatitis (NASH)
- Prolonged exposure to environmental toxins such as arsenic
Liver fibrosis symptoms include,
- Abdominal pain
- Abnormal accumulation of fluid in the abdominal cavity (ascites)
- Bleeding from engorged veins in the esophagus or intestines
- Dark, cola-colored urine
- Easy bruising
- Exhaustion
- Fatigue
- Itchy hands and feet
- Lack of appetite
- Loss of interest in sex
- Nausea
- Small, spider-like blood vessels under the skin
- Swelling of legs and feet from retained fluid (edema)
- Tenderness and enlargement of the liver
- Weakness
- Weight loss
- Yellowing of skin and eyes (jaundice)
For more information, see cirrhosis.
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